Universität zu Köln 

Prof. Dr. Sabine Zachgo

Universität Osnabrück
(formerly: Max-Planck-Institut für Pflanzenzüchtungsforschung, Köln)
email: sabine.zachgo@biologie.uni-osnabrueck.de
phone: +49-(0)541 969 2840?
website

Running time: 2007 – 2009

Abstract

Glutaredoxins (GRXs) are ubiquitous oxidoreductases that exert a crucial function in the response to oxidative stress. GRXs modify target proteins posttranslationally and reduce mixed disulfides by way of conserved cysteines located in active site motifs. We have recently characterised the first Arabidopsis mutant for a plant-specific GRX named ROXY1, revealing a floral phenotype affecting petal formation. We are aiming to identify and analyse proteins that are posttranslationally modified by ROXY1 in order to understand how plant-specific GRXs and redox regulation contribute to the control of flower development.

(A final report will follow.)

Publications resulting from the project:

Li, S., Lauri, A., Ziemann, M., Busch, A., Bhave, M. and Zachgo, S. (2009). Nuclear activity of ROXY1, a glutaredoxin interacting with TGA factors, is required for petal development in Arabidopsis thaliana. Plant Cell 21, 429-441.

Ziemann, M., Bhave, M. and Zachgo, S. (2009). Origin and diversification of land plant CC-type glutaredoxins. Genome Biol. and Evol. 1, 1-12.

Wang, Z., Xing, S., Birkenbihl, R.P. and Zachgo, S. (2009). Conserved functions of Arabidopsis and rice CC-type glutaredoxins in flower development and pathogen response. Mol. Plant 2, 323-335.

Li, S. and Zachgo, S. (2009). Glutaredoxins in development and stress responses of plants. Advances in Botanical Research 52, 335-403.

Xing, S. and Zachgo, S. (2008). ROXY1 and ROXY2, two CC type glutaredoxin genes, together control anther development in Arabidopsis thaliana. Plant J. 53, 790-801.

Xing, S. and Zachgo, S. (2007). Pollen lethality: a phenomenon in Arabidopsis RNA interference plants. Plant Physiol. 145, 330-333.